Insights into all aspects of drug discovery, design and development

Why Pharma needs a new business model to fight antimicrobial resistance

The ability of bacteria and fungi to develop resistance to antimicrobial treatments isn’t a new phenomenon; we’ve observed the effects since the discovery of the first antibiotics almost a century ago. Antibacterial resistance is an inevitable consequence of natural selection – and it shouldn’t be ...

Topics: Antibiotic Resistance, Antibacterial Read More

What's the secret to successful drug formulation?

Drug formulation plays a vital role in the success of any pharmaceutical development program. From early preclinical investigations through to late stage clinical trials, formulation chemistry is used throughout the development process and is essential for the design of a safe and effective ...

Topics: Drug Development Read More

Quality by Design in drug development

A more systematic approach to drug development There are few environments where quality control is more important than in drugmanufacturing. Medicines must be safe to use and deliver a consistent clinical effect to treat the targeted disease. However, even with the most robust quality control ...

Topics: Drug Development, Drug Discovery Read More

Adopt a considered screening strategy for your hit identification campaign

Developing robust and reliable high-throughput screening assays High-throughput screening (HTS) plays a pivotal role in drug discovery. It’s used to hunt for ‘hits’ – those sought-after molecules that modulate the activity of targeted biological pathways. Hits can progress through the pipeline to ...

Topics: Drug Discovery, High Throughput Screening Read More

The challenges you must consider when developing a drug for pulmonary delivery

Lung diseases such as asthma, idiopathic pulmonary fibrosis and chronic obstructive pulmonary disease (COPD) are a growing global healthcare challenge, with figures suggesting they are responsible for around one in ten deaths in the EU. For those developing treatments for these chronic respiratory ...

Topics: Drug Development, Drug Discovery, Respiratory Read More