Insights into all aspects of drug discovery, design and development

The challenges you must consider when developing a drug for pulmonary delivery

Lung diseases such as asthma, idiopathic pulmonary fibrosis and chronic obstructive pulmonary disease (COPD) are a growing global healthcare challenge, with figures suggesting they are responsible for around one in ten deaths in the EU. For those developing treatments for these chronic respiratory ...

Topics: Drug Development, Drug Discovery, Respiratory Read More

Antibiotic resistance is a global challenge that must be met with a global response

Antibiotic resistance poses one of the biggest threats to public health in modern times. Currently, an estimated 50,000 deaths across Europe and the US ever year are thought to be caused by antibiotic resistance. If left unchecked, experts believe that resistance to antimicrobial drugs could result ...

Topics: Drug design and discovery, Drug Discovery, Antibacterial Read More

Could an over-reliance on computational PAINS filters prove a costly mistake for drug discovery?

  High throughput screening (HTS) has long played a vital role in drug discovery within the pharmaceutical industry, and its use in academia is growing too. These large-scale assays are used to screen thousands of compounds in search of hits – those sought after compounds that are used as starting ...

Topics: Drug Discovery, High Throughput Screening Read More

How to identify if you need outside expertise for Active Pharmaceutical Ingredient (API) development

Your API strategy: How to identify if you need additional resource  Your API fuels your drug development program, which is likely to suffer if you allow it to become depleted. It is, of course, advisable therefore to consider whether you have the resources to synthesize the quantities of the API ...

Topics: Active Pharmaceutical Ingredient Read More

Integrating Active Pharmaceutical Ingredient program into drug discovery and drug development

Integrating API – Not limited to drug development Both drug discovery and drug development are critical to the identification of novel medicines that may at one point in the future have a significant impact on global health. There are many variables that go into the processes, such as the defining ...

Topics: Active Pharmaceutical Ingredient Read More