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Serge Parel

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Recent Posts


How to ensure your high throughput screening program is a resource-efficient hit
Serge Parel, 19 September 2017

High throughput screening (HTS) has long been an important first step in the search for new drug molecules. Here, the goal is to identify high-quality hits that can be easily optimized into lead compounds and ultimately, safe and effective medicines. In recent years HTS has become something of a numbers game – after all, with a larger screening...

Could an over-reliance on computational PAINS filters prove a costly mistake for drug discovery?
Serge Parel, 23 May 2017

  High throughput screening (HTS) has long played a vital role in drug discovery within the pharmaceutical industry, and its use in academia is growing too. These large-scale assays are used to screen thousands of compounds in search of hits – those sought after compounds that are used as starting points in the development of novel...



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