Insights into all aspects of drug discovery, design and development

Improving the translational relevance of preclinical models for pulmonary fibrosis

Preclinical models play a vital role in understanding the potency, efficacy and safety of new pharmaceutical products, allowing developers to make timely decisions on the progression of drug candidates. Given their importance for de-risking development programs, it’s essential preclinical models ...

Topics: Drug Development Read More

Reducing attrition in drug discovery using improved candidate selection strategies and more translational models

Attrition in drug development has long been an issue for pharma.Despite passing industry trends and pipeline developments, it’s one that isn’t going away. To discuss solutions to this key challenge, experts from pharma and biotech met in Boston on December 4th 2017 for the concluding workshop in ...

Topics: Drug Development Read More

Three ways to manage risk in drug development

Drug development can sometimes feel a little like a ski holiday in the Swiss Alps: an inherently costly and risky venture. Indeed, even a well-seasoned developer can soon find costs have snowballed, timelines have slipped, and a veritable mountain of resources has been invested in a program that ...

Topics: Drug Development Read More

Overcoming tomorrow’s formulation challenges to deliver the medicines of the future

What strategies and technologies should we adopt if we’re to turn today’s promising drug molecules into tomorrow’s safe, effective and affordable medicines? That was the focus of the discussion at Aptuit’s one-day workshop, Improving Candidate Selection Strategies: Translating Molecules into ...

Topics: Drug Development Read More

Formulation strategies for oral bioavailability enhancement

With tablets and capsules convenient for patients to take and cost-effective to manufacture, it’s little wonder that oral delivery is the preferred route of administration for most pharmaceutical development projects. Yet current discovery strategies are increasingly resulting in larger, more ...

Topics: Drug Development Read More